First Descents (FD), the nonprofit that provides outdoor adventures for young adults impacted by cancer and other severe health conditions, announced in a LinkedIn post on Thursday evening, May 15, that the organization’s CEO Ryan O’Donoghue took his own life on May 9, 2025, after battling a long and severe mental health illness.
FD said O’Donoghue was more than a leader, “he was a source of inspiration, compassion and unwavering dedication to the communities he championed. His energy, warmth and vision touched everyone who had the privilege of working with him or knowing him. We are holding Ryan’s family and loved ones close in our hearts, and our deepest sympathies are with them during this unimaginable time,“ the organization wrote.”
“Ryan’s unwavering commitment to the young adult community, including those facing cancer, MS and other health challenges, was not just professional, it was shaped by his own lived experience. Many of you shared life-changing moments with him on programs, around campfires or in heartfelt conversations. He was moved by your strength and your stories, as well as by the power of healing adventures. As we grieve this loss together, please know that the spirit of what Ryan built — with and for you — will live on in every First Descents experience. We will continue to honor his legacy by showing up for each other with vulnerability, courage and love,“ the FD team shared.
O’Donoghue joined FD as executive director in 2013, following a tenure managing major gifts, grants and corporate partners for the Livestrong Foundation. Before losing his brother Colin to young adult cancer, he had founded the nonprofit Rise Above It to address the increasing need of the adolescent and young adult oncology community.
Under his leadership, First Descents said it experienced considerable growth, allowing the organization to provide over 13,000 participant experiences.
In his early career, O’Donoghue worked in Accenture’s Strategy Practice, managing Fortune 500 client accounts across several industries. He held a B.S.B.A. in Finance and Technology Management from Georgetown University, where he was captain of the football team and an Academic All-American in 2000.
Effective immediately, First Descents Founder and previous CEO Brad Ludden has resumed the CEO role and will collaborate closely with First Descents’ board of directors and partners. All 2025 programs and activities are underway and will progress without disruption.
“At First Descents, we remain focused on fostering a community where mental health is prioritized, stigma is dismantled and support is always available,“ the organization wrote. “This loss has touched us all, as it’s a heartbreaking reminder that none of us are immune to emotional pain, no matter our role, success or dedication to helping others.”
The organization continued, “If you are struggling, please know you are not alone. There is no shame in asking for help—only courage. Please consider taking a moment today to care for your own well-being, whether it’s reaching out to someone you trust, scheduling time to rest, or connecting with a mental health professional.”
If you or someone you care about is experiencing a mental health issue, First Descents encourages us all to call 988 to speak with someone 24/7.
Images courtesy First Descents
