New York lawmakers on Tuesday approved the toughest gun control law in the nation, expanding the state’s existing assault weapons ban and addressing gun ownership by those with mental illnesses. The law marks the first major legislative action in response to the Newtown, CO. school massacre.

The measure passed the state Assembly 104-43 after passing the state Senate 43-18 Monday. Gov. Andrew Cuomo quickly signed the legislation on Tuesday.

“This unfortunately required tragedies and loss of life to actually spur the political process to action,” Cuomo said in remarks minutes before signing the bill.

“This will be the toughest gun control package in the nation,” Sen. Jeffrey Klein, leader of the Independent Democratic Conference that shares majority control with Republican senators, had told The Associated Press. “All in all, it is a comprehensive, balanced approach that will save lives.”